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ACROBiosystems Human CD30 / TNFRSF8 Protein, His Tag

Brand:  ACROBiosystems CD0-H52H5-1mg

Additional Details : Weight : 0.00010kg

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Product Code. 17206080

  • 22297.28 SEK / 1mg
Estimated Shipment: 07-05-2024
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Description

Description

Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 40.4 kDa.
Specifications

Specifications

NP_001234.2
1 mg
Phe 19 - Lys 379
TNFRSF8,CD30,D1S166E,Ki-1
Unconjugated
His Tag
Powder
40.4 kDa
Human CD30, His Tag (CD0-H52H5) is expressed from human 293 cells (HEK293). It contains AA Phe 19 - Lys 379 (Accession # NP_001234.2).
-20°C
CD30
Human
HEK293
Immune Checkpoint Proteins
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