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Invitrogen™ Human CDNF Synthetic Peptide
Beskrivning
CDNF Synthetic Peptide, PEP-0546, from Invitrogen.
The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain. Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6 OHDA) induced degeneration of dopaminergic neurons in a rat model of Parkinsons disease. Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinsons disease. At least two isoforms of CDNF are known to exist.
Specifikationer
Specifikationer
| Gen-ID (Entrez) | 441549 |
| Art | Human |
| Reningsmetod | purified |
| Tillträdesnummer | Q49AH0 |
| Vanligt namn | Human CDNF |
| Koncentration | 200 μg/mL |
| Innehåll och lagring | -20°C |
| Beskrivning | Synthetic Peptide |
| Formatera | Liquid |
| Formulering | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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Produkttitel
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