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Gibco™ Human FGF-4 Recombinant Protein

Produktkod. 10009132
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Kvantitet:
25 μg
Förpackningsstorlek:
Varje
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Produktkod. Kvantitet unitSize
10009132 25 μg Varje
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For Research Use Only. All usage must comply with product instructions.
Produktkod. 10009132 Leverantör Gibco™ Leverantörsnummer PHG0154
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    6040.00 SEK
    5798.40 SEK / 25µg
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Beräknad leverans: 24-08-2026
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For Research Use Only. All usage must comply with product instructions.

Beskrivning

Recombinant Protein

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2°C to 8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein, such as 0.1% BSA and store in working aliquots at -20°C to -80°C. Storage: The lyophilized protein is stable at room temperature for 1 month, but should be kept at -20°C for long term storage, preferably desiccated. Working aliquots stored with a carrier protein are stable for at least 3 months at -80°C to -20°C. Avoid repeated freeze/thaw cycles.

Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.
TRUSTED_SUSTAINABILITY

Specifikationer

Tillträdesnummer P08620
För användning med (applikation) Bioactivity
Formulering 10mM sodium phosphate with 100mM NaCl and no preservative; pH 7.4
Gen-ID (Entrez) 2249
Molekylvikt (g/mol) 19.7 kDa
Namn Human FGF-4
pH-intervall 7.4
Reningsmetod Purified
Kvantitet 25 μg
Förvaringskrav -20°C
Regulatorisk status RUO
Endotoxinkoncentration <0.1 ng/μg
Gene Alias FGF; FGF4; Fgf-4; Fgfk; Fibroblast growth factor; fibroblast growth factor 4; fibroblast growth factor 4 splice isoform; HBGF-4; heparin secretory transforming protein 1; heparin secretory-transforming protein 1; heparin-binding growth factor 1; heparin-binding growth factor 4; HST; Hst1; hst-1; HSTF1; HSTF-1; human stomach cancer, transforming factor from FGF-related oncogene; kaposi sarcoma oncogene; Kfgf; K-FGF; K-fibroblast growth factor; KS3; oncogene HST; transforming protein KS3
Vanligt namn FGF4
Gensymbol Fgf4
Biologisk aktivitet ED50 ≤ 10 ng/mL; determined by the dose-dependent proliferation of Balb/c 3T3 cells.
Produkttyp Protein
Konjugera Unconjugated
Art Human
Rekombinant Recombinant
Sekvens Human FGF-4 recombinant protein contains 182 amino acids
Innehåll och lagring -20°C
Aktivitet ED50 ≤ 10 ng/mL; determined by the dose-dependent proliferation of Balb/c 3T3 cells.
Endotoxinnivå <0.1 ng/μg
Frakt skick Approved for shipment on Wet or Dry Ice
Uttryckssystem E. coli
Proteinfamilj Growth Factors & Receptors
Proteinform Recombinant, Ligand
Form Lyophilized
Protein subtyp FGFs (Fibroblast Growth Factors)
Forskningskategori Neurobiology, Oncology, Stem Cell Research, Microbiology, Differentiation, Angiogenesis
Produktlinje Gibco
Renhet eller kvalitetsklass ≥95% by SDS-PAGE and HPLC
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