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Gibco™ Human Heregulin beta-1 Recombinant Protein, PeproTech®
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Kvantitet:
1 mg
10 μg
100 μg
250 μg
50 μg
500 μg
Förpackningsstorlek:
100µg
10µg
Beskrivning
Recombinant Human Heregulin beta-1 (HRG1-B1) is a 7.5 kDa polypeptide consisting of only the EGF domain of heregulin beta-1 (65 amino acid residues). This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.
Specifikationer
Specifikationer
| Tillträdesnummer | Q02297 |
| För användning med (applikation) | ELISA, Functional Assay, Western Blot |
| Formulering | protein with no preservative |
| Gen-ID (Entrez) | 3084 |
| Molekylvikt (g/mol) | 7.5 kDa |
| Namn | Human Heregulin beta-1 |
| Kvantitet | 10 μg |
| Källa | E. coli |
| Regulatorisk status | RUO |
| Endotoxinkoncentration | <1 EU/ μg |
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