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Gibco™ Human HGF Recombinant Protein, PeproTech®
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Kvantitet:
10 μg
100 μg
2 μg
2 x 250 μg
250 μg
4 x 250 μg
50 μg
Förpackningsstorlek:
10µg
Beskrivning
100-39-1MG will be provided as 4 x 250 μg (100-39-250UG). 100-39-500UG will be provided as 2 x 250 μg (100-39-250UG). Recombinant Human HGF is an 80.0 kDa polypeptide consisting of 697 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.
Specifikationer
Specifikationer
| Tillträdesnummer | P14210 |
| För användning med (applikation) | Functional Assay |
| Formulering | protein with no preservative |
| Gen-ID (Entrez) | 3082 |
| Molekylvikt (g/mol) | 80 kDa |
| Namn | Human HGF |
| Kvantitet | 100 μg |
| Källa | Insect cells |
| Regulatorisk status | RUO |
| Endotoxinkoncentration | <1 EU/μg |
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