missing translation for 'onlineSavingsMsg'
Läs mer
  1. Home
  2. Products
  3. Rekombinanta proteiner
  4. 10005793

Invitrogen™ Human IFN-alpha 2 (alpha 2b) Recombinant Protein

Produktkod. 10005793
Change view
Klicka för att se tillgängliga alternativ
Kvantitet:
1 x 10^5 units
Förpackningsstorlek:
Varje
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Produktkod. Kvantitet unitSize
10005793 1 x 10^5 units Varje
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Denna artikel kan inte returneras. Se returpolicy
Produktkod. 10005793 Leverantör Invitrogen™ Leverantörsnummer 111051

Please to purchase this item. Need a web account? Register with us today!

Denna artikel kan inte returneras. Se returpolicy

Beskrivning

Recombinant Protein

After receipt, the product may be stored at -20°C for short-term use (less than 6 months). For long-term storage, store the product at -70°C or below for retention of full activity. Thaw product vial by incubation in cold tap water until just thawed. Aliquot and refreeze unused contents to minimize effects of freeze thawing. Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of product should be in buffers containing protein such as 0.1% BSA or tissue culture media with serum.

Interferon alpha-2b is a cytokine that belongs to the type I interferon family and is encoded by a gene cluster on chromosome 9. It is produced in response to viral infection and plays a key role in the innate immune response, exhibiting potent antiviral, antiproliferative and immunomodulatory properties. Interferon alpha-2b binds to a plasma membrane receptor consisting of IFNAR1 and IFNAR2, which is expressed ubiquitously in the body and can thus act on virtually all cells. This cytokine is effective in reducing the symptoms and duration of the common cold, and has shown efficacy in treating various types of cancer, including hematological malignancies and solid tumors. A deficiency of type I interferon in the blood is considered a hallmark of severe COVID-19, and a combination therapy involving interferon alpha-2b may be a potential therapeutic approach. IFNA2 has been associated with diseases such as Severe Covid-19 and Hepatitis B.
TRUSTED_SUSTAINABILITY

Specifikationer

Tillträdesnummer P01563
Koncentration Lot-specific
För användning med (applikation) ELISA
Formulering PBS with 0.1% BSA and no preservative
Gen-ID (Entrez) 3440
Molekylvikt (g/mol) 19.3 kDa
Namn Human IFN-alpha 2 (alpha 2 b)
Kvantitet 1 x 10^5 units
Källa E. Coli
Regulatorisk status RUO
Endotoxinkoncentration <1 EU/ μg
Gene Alias alpha-2 A interferon; IFNA; IFNA2; IFNA2A; IFNA2B; IFNA2C; IFN-alpha-2; IFN-alphaA; INFA2; Interferon; interferon alpha 2; interferon alpha 2 A; interferon alpha 2 b; interferon alpha A; interferon alpha-2; Interferon alpha-A; interferon, alpha 2; leIF A
Vanligt namn Interferon alpha-2 b
Gensymbol IFNA2
Biologisk aktivitet EC50 ̃ 1 U/mL; determined by use of the cytopathic effect inhibition assay described in [Rubinstein, S. et al. (1981). J. Virol. 37, 755-758 ]; [Familletti, P.C. et al. (1981). Methods in Enzymology, Vol. 78, 387-394 ]. The units are determined with respect to the international reference standard for human interferon alpha A (Hu-IFN-alpha-A) provided by the National Institutes of Health [see Pestka, S. (1986). Methods in Enzymology, Academic Press, New York 119, 14-23 ]. Unit of activity measured on bovine MDBK cells with vesicular stomatitis virus (VSV).
Konjugera Unconjugated
Art E. coli
Rekombinant Recombinant
Innehåll och lagring -80°C, Avoid Freeze/Thaw Cycles
Uttryckssystem E. coli
Form Liquid
Protein subtyp Recombinant
Renhet eller kvalitetsklass >95%
Visa mer Visa mindre
Produkttitel
Välj ett problem

Genom att klicka på Skicka bekräftar du att du kan bli kontaktad av Fisher Scientific angående feedbacken du har lämnat i detta formulär. Vi kommer inte att dela din information för andra ändamål. All kontaktinformation som tillhandahålls ska också underhållas i enlighet med vår Sekretesspolicy.