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Gibco™ Human IL-19, Animal-Free Recombinant Protein, PeproTech®

Product Code. 30019710
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Kvantitet:
1 mg
10 μg
100 μg
2 μg
250 μg
500 μg
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Product Code. 30019710

Brand: Gibco™ AF20019250UG

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14274.00 SEK valid until 2025-12-19
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Description

Recombinant Protein

Recombinant Human IL-19 is a 35.8 kDa homodimer of two 154 amino acid chains. In solution, IL-19 exists predominantly as a non-disulfide-linked dimer.

The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.
TRUSTED_SUSTAINABILITY

Specifications

Tillträdesnummer Q9UHD0
För användning med (applikation) Functional Assay
Formatera Lyophilized
Formulering protein with no preservative
Gen-ID (Entrez) 29949
Molekylvikt (g/mol) 35.8 kDa
Namn Human IL-19, Animal-Free
Kvantitet 250 μg
Regulatorisk status RUO
Endotoxinkoncentration <1 EU/ μg
Gene Alias il 19; IL-10 C; IL19; IL-19; ILN; Interleukin; interleukin 19; Interleukin19; interleukin-19; MDA1; MDA-1; melanoma differentiation associated protein-like protein; melanoma differentiation-associated protein-like protein; NG0.1; ZMDA1
Vanligt namn IL-19
Biologisk aktivitet Determined by its ability to stimulate the proliferation of HEK-Blue TM-IL-19 reporter cells
Konjugera Unconjugated
Rekombinant Recombinant
Sekvens MLRRCLISTD MHHIEESFQE IKRAIQAKDT FPNVTILSTL ETLQIIKPLD VCCVTKNLLA FYVDRVFKDH QEPNPKILRK ISSIANSFLY MQKTLRQCQE QRQCHCRQEA TNATRVIHDN YDQLEVHAAA IKSLGELDVF LAWINKNHEV MSSA
Innehåll och lagring -20°C
Uttryckssystem E. coli
Form Lyophilized
Renhet eller kvalitetsklass ≥ 98% by SDS-PAGE gel and HPLC analyses.
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