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Gibco™ Human IL-2 Recombinant Protein, PeproTech®

Produktkod. 17881063
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Produktkod. Kvantitet unitSize
17881063 100 μg -
17851193 10 μg 10µg
17820813 1 mg -
17850213 250 μg -
17881773 500 μg -
17831293 50 μg 50µg
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Produktkod. 17881063 Leverantör Gibco™ Leverantörsnummer 20002100UG

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2246.75 SEK valid until 2026-02-28
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Beskrivning

Recombinant Protein

Recombinant Human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
TRUSTED_SUSTAINABILITY

Specifikationer

Tillträdesnummer P60568
För användning med (applikation) ELISA, Functional Assay, Western Blot
Formulering protein with no preservative
Gen-ID (Entrez) 3558
Molekylvikt (g/mol) 15.5 kDa
Namn Human IL-2
Kvantitet 100 μg
Källa E. coli
Regulatorisk status RUO
Endotoxinkoncentration <1 EU/ μg
Gene Alias aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
Vanligt namn IL-2
Gensymbol IL2
Biologisk aktivitet The ED50 as determined by the dose-dependent stimulation of murine CTLL-2 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10^7 units/mg
Konjugera Unconjugated
Rekombinant Recombinant
Sekvens MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFAQSII STLT
Innehåll och lagring -20°C
Uttryckssystem E. coli
Form Lyophilized
Renhet eller kvalitetsklass ≥ 98% by SDS-PAGE gel and HPLC analyses.
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