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Invitrogen™ MCP-1 Human ELISA Kit

For the quantitative detection of human MCP-1.

Brand:  Invitrogen™ BMS281TEN

Additional Details : Weight : 0.23750kg

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Product Code. 15571877

  • 30380.00 SEK / Pack of 10


Estimated Shipment
14-12-2020
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Includes: Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human MCP-1
HRP-Conjugate anti-human MCP-1 monoclonal antibody
Human MCP-1 Standard lyophilized, 2ng/mL upon reconstitution
Control high, lyophilized
Control low, lyophilized
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Adhesive Films

Description

Description

MCP-1 (Monocyte chemotactic protein-1, CCL2) has a predicted molecular weight of approximately 11kDa, however, it may run at a higher molecular weight due to glycosylation. MCP-1 is a member of the cytokine family and plays an important role in immunoregulation and inflammatory processes. MCP-1 signals through G protein-coupled receptors, CCR2 and CCR4, to recruit memory T cells, monocytes and dendritic cells. MCP-1 is linked with tumor progression, angiogenesis, and displays selective chemotactic activity towards monocytes and basophils but not neutrophils or eosinophils. MCP-1 is produced by a variety of cell types and is a potent chemoattractant for monocytes, memory T lymphocytes, and natural killer (NK) cells. Further, MCP-1 is indicated in the etiology of several immune disorders, and is upregulated during infection and inflammation. While MCP-1 is a potent basophil activator, the related protein MCP-2 stimulates both eosinophils and basophils. MCP-3 has been shown to have the broadest range of influence. MCP-1 has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis.
Specifications

Specifications

P13500
HRP
6347
ELISA Kit
2.3 pg/mL
Amniotic Fluid, 20 μL|Plasma, 20 μL|Serum, 20 μL|Supernatant, 20 μL
1 hr. 20 min.
Human
Monocyte chemoattractant protein 1, MCAF, HC11
4.7%
Human
HRP
15.6-1,000 pg/mL
ELISA
Pre-coated 96 well plate, Standard, Sample Diluent, Assay Buffer concentrate, HRP-conjugated Detection Antibody, Wash Buffer, Chromogen, Stop Solution, Controls, Adhesive Plate Covers
RUO
20 μL
2°C to 8°C
2 hr. 10 min.
GDCF-2,HC11,HSMCR30,MCAF,MCP-1,MCP1,SCYA2,SMC-CF
8.7%
10 x 96 Tests
Supernatant
Colorimetric Microplate Reader
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For Research Use Only