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Gibco™ Human/Mouse/Rat Activin A Recombinant Protein, PeproTech®
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Kvantitet:
10 μg
100 μg
2 μg
2 x 500 μg
250 μg
50 μg
500 μg
Beskrivning
120-14P-1MG will be provided as 2 x 500 μg (120-14P-500UG). Recombinant Human/Murine/Rat Activin A is a 26.0 kDa disulfide-linked homodimer of two betaA chains, each containing 116 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Activin A mutations are associated with fibrodysplasia ossificans progressive.
Specifikationer
Specifikationer
| Tillträdesnummer | P08476, P18331, Q04998 |
| För användning med (applikation) | Functional Assay |
| Formulering | protein with no preservative |
| Gen-ID (Entrez) | 16323, 29200, 3624 |
| Molekylvikt (g/mol) | 26 kDa |
| Namn | Human/Mouse/Rat Activin A |
| Kvantitet | 10 μg |
| Källa | CHO cells |
| Regulatorisk status | RUO |
| Endotoxinkoncentration | <1 EU/ μg |
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