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Invitrogen™ Human Nectin-2 (CD112) Fc Chimera Recombinant Protein

Produktkod. 17926341
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Kvantitet:
1 mg
100 μg
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Produktkod. 17926341

Brand: Invitrogen™ RP87966

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Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (1493 μL) be added to the vial to prepare a stock solution of 0.67 mg/mL. Concentration is measured by UV.

This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
TRUSTED_SUSTAINABILITY

Specifikationer

Tillträdesnummer Q92692
Koncentration 0.25 mg/mL
För användning med (applikation) Control, ELISA Standard, Binding Assay
Formatera Lyophilized
Formulering PBS with 5% mannitol, 5% trehalose, 0.01% Tween 80 and no preservative; pH 7.4
Gen-ID (Entrez) 5819
Molekylvikt (g/mol) 70-80 kDa
Namn Human Nectin-2 (CD112) Fc Chimera
pH-intervall 7.4
Reningsmetod Purified
Kvantitet 100 μg
Förvaringskrav -20°C, Avoid Freeze/Thaw Cycles
Regulatorisk status RUO
Endotoxinkoncentration <1.0 EU/μg
Gene Alias AI325026; AI987993; CD112; herpes virus entry mediator B; Herpesvirus entry mediator B; herpesvirus entry protein B; hveB; mHveB; MPH; Murine herpes virus entry protein B; murine herpesvirus entry protein B; nectin cell adhesion molecule 2; Nectin2; Nectin-2; Poliovirus receptor homolog; poliovirus receptor related 2; poliovirus receptor-like 2; poliovirus receptor-related 2; poliovirus receptor-related 2 (herpesvirus entry mediator B); poliovirus receptor-related protein 2; poliovirus sensitivity; PRR2; Pvr; Pvrl2; PVRR2; Pvs
Vanligt namn Nectin 2
Gensymbol NECTIN2
Biologisk aktivitet 1. Measured by its binding ability in a functional ELISA. Immobilized human CD226 at 2 μg/ml (100 μL/well) can bind human CD112 with a linear range of 6.4-800 ng/mL 2. Immobilized PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His Tag) (at 2 μg/ml (100 μL/well) can bind Nectin-2 Protein, Human, Recombinant (hFc Tag), the EC50 of Nectin-2 Protein, Human, Recombinant (hFc Tag)is 0.2-1.2 ng/mL)
Produkttyp Protein
Konjugera Unconjugated
Rekombinant Recombinant
Protein Tag Fc-tag
Sekvens Human CD112, amino acids Met1-Leu360 (Accession # NP_002847.1) with a C-terminal human IgG1 Fc region
Innehåll och lagring -20°C, Avoid Freeze/Thaw Cycles
Aktivitet 1. Measured by its binding ability in a functional ELISA. Immobilized human CD226 at 2 μg/ml (100 μL/well) can bind human CD112 with a linear range of 6.4-800 ng/mL. 2. Immobilized PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His Tag) at 2 μg/ml (100 μL/well) can bind Nectin-2 Protein, Human, Recombinant (hFc Tag), the EC50 of Nectin-2 Protein, Human, Recombinant (hFc Tag)is 0.2-1.2 ng/mL.
Uttryckssystem HEK293 cells
Form Lyophilized
Renhet eller kvalitetsklass >95% as determined by SDS-PAGE.
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