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R&D Systems™ Human PCSK9 (NP_777596) VersaClone cDNA
Beskrivning
- Also known as: FH3; PC9; NARC1; LDLCQ1; NARC-1; HCHOLA3
- PCSK9 is a member of the subtilisinlike proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway.
- It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation.
- It plays a role in cholesterol and fatty acid metabolism.
- Mutations in PCSK9 have been associated with autosomal dominant familial hypercholesterolemia.
- Alternatively spliced transcripts encoding different proteins have been described.
- The insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
- For reasearch use only. Not for use in humans.
Specifikationer
Specifikationer
| Gen | Proprotein Convertase 9/PCSK9 |
| Tillträdesnummer | NP_777596 |
| Koncentration | 10 μg at 0.2 μg/μL |
| Formulering | cDNA is provided in 10 mM Tris-Cl, pH 8.5 |
| Infoga typ | 2092 bp |
| Gen-ID (Entrez) | 255738 |
| Gene Alias | EC 3.4.21, EC 3.4.21.111, FH3, FH3neural apoptosis regulated convertase 1, FHCL3, HCHOLA3, hypercholesterolemia, autosomal dominant 3, LDLCQ1, NARC1, NARC-1, NARC-1 convertase subtilisin/kexin type 9 preproprotein, NARC1EC 3.4.21.-, Neural apoptosis-regulated convertase 1, PC9, PCSK9, Proprotein convertase 9, proprotein convertase subtilisin/kexin type 9, Subtilisin/kexin-like protease PC9 |
| Innehåll och lagring | Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date. |
| Art | Human |
| Kvantitet | 10 μg |
Produkttitel
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