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Invitrogen™ Human PHAP III Synthetic Peptide

Produktkod. 15236369
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Kvantitet:
50 μg
Förpackningsstorlek:
50µg
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Produktkod. Kvantitet unitSize
15236369 50 μg 50µg
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Produktkod. 15236369 Leverantör Invitrogen™ Leverantörsnummer PEP0142
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Beräknad leverans: 24-08-2026
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Beskrivning

Synthetic Peptide

This peptide corresponds to amino acids near the carboxy terminus of human PHAP III. PEP-0142 can be used as a blocking peptide with polyclonal antibody PA5-20023.

Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
TRUSTED_SUSTAINABILITY

Specifikationer

Gen-ID (Entrez) 81611
Art Human
Reningsmetod purified
Tillträdesnummer P39687
Vanligt namn PHAP III
Koncentration 200 μg/mL
Innehåll och lagring -20°C
Beskrivning Synthetic Peptide
Formatera Liquid
Formulering PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
För användning med (applikation) Blocking Assay, Control
Gene Alias 2810018A15Rik; Acid nuclear phosphoprotein 32 (leucine rich); acidic (leucine-rich) nuclear phosphoprotein 32 family, member A; acidic (leucine-rich) nuclear phosphoprotein 32 family, member E; acidic leucine-rich nuclear phosphoprotein 32 family member A; Acidic leucine-rich nuclear phosphoprotein 32 family member E; Acidic leucine-rich nuclear phosphoprotein 32 family member E-like protein; acidic nuclear phosphoprotein 32; acidic nuclear phosphoprotein 32 family member A; acidic nuclear phosphoprotein 32 family member E; acidic nuclear phosphoprotein 32 family, member A; acidic nuclear phosphoprotein pp32; AI047746; AI326868; Anp32; Anp32a; Anp32e; C15orf1; cerebellar leucine rich acidic nuclear protein; cerebellar postnatal development protein 1; Cpd1; hepatopoietin Cn; HPPCn; I1PP2A; inhibitor-1 of protein phosphatase-2A; LANP; LANPL; LANP-L; LANP-like protein; Leucine-rich acidic nuclear protein; leucine-rich acidic nuclear protein LANP; leucine-rich acidic nuclear protein like; MAPM; Mapmodulin; mLANP-L; PHAP1; PHAPI; Potent heat-stable protein phosphatase 2A inhibitor I1PP2A; pp32; Putative HLA-DR-associated protein I; putative human HLA class II associated protein I; RP4-790G17.1; vacidic (leucine-rich) nuclear phosphoprotein 32 family, member A; W91701; wu:fb22e03; wu:fc04c12; wu:fc19a08; wu:fc79f04; wu:fi39c10; zgc:65995; zgc:85827
Gensymbol ANP32A
Frystorkat material No
Konserveringsmedel Sodium azide
Produkttyp Peptide
Kvantitet 50 μg
Regulatorisk status RUO
Förvaringsbuffert PBS
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