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Gibco™ Human R-Spondin 1 Recombinant Protein, PeproTech®

Produktkod. 30088098
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30088098 2 x 500 μg -
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Produktkod. 30088098 Leverantör Gibco™ Leverantörsnummer 1203801M
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Description

Recombinant Protein

120-38-1MG will be provided as 2 x 500 μg (120-38-500UG). Recombinant Human R-Spondin-1 is a 26.7 kDa protein consisting of 243 amino acid residues. Due to glycosylation, R-Spondin-1 migrates at an apparent molecular weight of approximately 40.0 kDa by SDS-PAGE analysis under reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis.

This gene is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.
TRUSTED_SUSTAINABILITY

Specifications

Tillträdesnummer Q2MKA7
För användning med (applikation) Bioactivity, Control
Formulering Protein with no preservative
Gen-ID (Entrez) 284654
Molekylvikt (g/mol) 26.7 kDa
Namn Human R-Spondin 1
Reningsmetod Purified
Kvantitet 2 x 500 μg
Källa CHO cells
Förvaringskrav -20°C
Regulatorisk status RUO
Endotoxinkoncentration <1 EU/μg
Gene Alias CRISTIN3; cristin-3; cysteine-rich and single thrombospondin domain-containing protein 3; FLJ40906; hRspo1; mCristin-3; RGD1565558; Roof plate-specific spondin-1; RP11-566C13.1; RSPO; RSPO1; Rspondin; R-spondin; R-spondin 1; R-spondin homolog; R-spondin homolog (Xenopus laevis); R-spondin-1; thrombospondin type 1 domain containing gene Rspondin
Vanligt namn RSPO1
Gensymbol RSPO1
Biologisk aktivitet R-Spondin-1 enhances BMP-2-mediated differentiation of MC3T3-E1 cells. The expected ED50 is 1.0-3.0 ug/ml
Produkttyp Protein
Konjugera Unconjugated
Rekombinant Recombinant
Sekvens SRGIKGKRQR RISAEGSQAC AKGCELCSEV NGCLKCSPKL FILLERNDIR QVGVCLPSCP PGYFDARNPD MNKCIKCKIE HCEACFSHNF CTKCKEGLYL HKGRCYPACP EGSSAANGTM ECSSPAQCEM SEWSPWGPCS KKQQLCGFRR GSEERTRRVL HAPVGDHAAC SDTKETRRCT VRRVPCPEGQ KRRKGGQGRR ENANRNLARK ESKEAGAGSR RRKGQQQQQQ QGTVGPLTSA GPA
Innehåll och lagring -20°C
Aktivitet R-Spondin-1 enhances BMP-2-mediated differentiation of MC3T3-E1 cells. The expected ED50 is 1.0-3.0 ug/ml.
Uttryckssystem CHO cells
Form Lyophilized
Renhet eller kvalitetsklass ≥ 95% by SDS-PAGE gel and HPLC analyses.
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