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STEMCELL Technologies Human Recombinant VEGF-121
Vascular endothelial growth factor
Brand: STEMCELL Technologies 78127.1
Additional Details : Weight : 0.00110kg
Description
- Vascular endothelial growth factor (VEGF-121) is a naturally-occurring VEGF-A splice variant involved in embryonic vasculogenesis and angiogenesis
- VEGF binds to VEGFR-1 and VEGFR-2, and activates Raf/MEK/ERK and PI3K/AKT pathways
- VEGF-121 is released as a freely diffusible protein by a variety of normal and transformed cells
- It plays an important role in neurogenesis both in vitro and in vivo (Storkebaum et al.) It has neurotrophic effects on neurons of the central nervous system and promotes growth and survival of dopaminergic neurons and astrocytes
- VEGF also promotes growth and survival of vascular endothelial cells, monocyte chemotaxis, and colony formation by granulocyte-macrophage progenitor cells (Ferrara et al.)
Specifications
| MGC70609, MVCD-1, Vascular endothelial growth factor, Vascular endothelial growth factor 2, Vascular endothelial growth factor A, Vascular permeability factor, VEGFA, VPF | |
| ≥95% | |
| 100 μg | |
| Angiogenic Cells; Endothelial Cells; Hematopoietic Stem and Progenitor Cells; Mesenchymal Stem and Progenitor Cells; Mesoderm, PSC-Derived; Neural Stem and Progenitor Cells; Pluripotent Stem Cells |