Invitrogen™ eBioscience™ Human sICAM-1 Platinum ELISA Kit, extra sensitive
For the quantitative detection of human sICAM-1. Due to unique Antibody properties, this ELISA has increased sensitivity without further Amplification steps required.
Brand: Invitrogen™ BMS241
Additional Details : Weight : 0.23750kg
DescriptionICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.
|Pre-coated 96 well plate, Standard, Sample Diluent, Assay Buffer concentrate, HRP-conjugated Detection Antibody, Wash Buffer, Chromogen, Stop Solution, Controls, Adhesive Plate Covers|
|100μL (1:100 prediluted)|
|1 hr 20 min|
|Intercellular adhesion molecule 1, CD54 antigen|
|Colorimetric Microplate Reader|
|Amniotic Fluid, Bile, Plasma, Serum, Supernatants, Urine|
|Amniotic Fluid (100μL), Bile (100μL), Plasma (10μL), Serum (10μL), Supernatants (100μL), Urine (100μL)|
|2 hr 10 min|
For Research Use Only