missing translation for 'onlineSavingsMsg'
Learn More

Invitrogen™ TGF beta-1 Human ELISA Kit

For the quantitative detection of human TGF-beta1.

Brand:  Invitrogen™ BMS249-4

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15561827

  • 5110.00 SEK / 96 tests


In stock, ready to ship: 7
Add to basket

Includes: Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human TGF-beta1
Biotin-Conjugate anti-human TGF-beta1 monoclonal antibody
Streptavidin-HRP
Human TGF-beta1 Standard lyophilized, 4ng/mL upon reconstitution
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Adhesive Films

Description

Description

TGF beta-1 (TGFB1, Transforming Growth Factor Beta 1) is a polypeptide member of the transforming growth factor beta superfamily of cytokines, found almost ubiquitously in tissues. Transforming growth factor (TGF)-b is stored in the extracellular matrix as a latent complex with its pro-domain. Activation of TGF beta-1 requires the binding of aV integrin to an RGD sequence in the prodomain and exertion of force on this domain, which is held in the extracellular matrix by latent TGF-b binding proteins. Latent forms are complexes of TGF beta-1, an amino-terminal portion of the TGF-beta precursor, designated TGF-LAP (TGF-latency associated peptide), and a specific binding protein, known as LTBP. TGF beta-1 helps regulates proliferation, differentiation, adhesion, migration in many cell types. Many cells have TGF beta receptors, and the protein positively and negatively regulates many other growth factors. TGF beta-1 is cleaved into a latency-associated peptide and a mature TGF beta-1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGF beta-1 homodimer. The mature peptide may also form heterodimers with other TGF beta family members. The gene for TGF beta-1 is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease and cystic fibrosis.
Specifications

Specifications

P01137
Biotin
7040
ELISA Kit
8.6 pg/mL
Plasma, 20 μL|Serum, 20 μL|Supernatant, 20 μL
1 hr. 20 min.
Human
Camurati-Engelmann disease, DPD1
3.2%
Human
HRP
31-2,000 pg/mL
ELISA
Pre-coated 96 well plate, Standard, Sample Diluent, Assay Buffer concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
RUO
40 μL (pretreated)
2°C to 8°C
4 hr. 30 min.
CED,DPD1,LAP,TGFB,TGFbeta
4.9%
96 Tests
Supernatant
Colorimetric Microplate Reader
Videos
SDS
Documents