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Gibco™ Human VEGF-165, Animal-Free Recombinant Protein, PeproTech®

Produktkod. 17893383
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Produktkod. Kvantitet
17893383 10 μg
17813753 100 μg
17813623 1 mg
17883463 500 μg
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Produktkod. 17893383 Leverantör Gibco™ Leverantörsnummer AF1002010UG

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1912.00 SEK valid until 2026-06-30
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Beskrivning

Recombinant Protein

Recombinant Human VEGF 165 is a 38.2 kDa, disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

The vascular endothelial growth factor (VEGF) family currently includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. VEGF and its receptor system have been shown to be the fundamental regulators in the cell signaling of angiogenesis. Most tumors have the absolute requirement of angiogenesis and VEGF has been described as the most potent angiogenic cytokine linked to this process. To date 5 different isoforms of VEGF have been described. These isoforms are generated as the result of alternative splicing from a single VEGF gene. These various isoforms have been shown to bind to two tyrosine-kinase receptors flt-1 (VEGFR-1) and flk-1/KDR (VEGFR-2), which have been found to be expressed almost exclusively on endothelial cells.
TRUSTED_SUSTAINABILITY

Specifikationer

Tillträdesnummer P15692
För användning med (applikation) Functional Assay
Formulering protein with no preservative
Gen-ID (Entrez) 7422
Molekylvikt (g/mol) 38.2 kDa
Namn Human VEGF-165, Animal-Free
Kvantitet 10 μg
Källa E. coli
Regulatorisk status RUO
Endotoxinkoncentration <0.1 EU/ μg
Gene Alias H-VEGF-165; MVCD1; M-VEGF-165; vascular endothelial growth factor 165 b; vascular endothelial growth factor A; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular permeability factor; VEGF; VEGF164; VEGF165; Vegfa; VEGF-A; VPF
Vanligt namn VEGF-165
Gensymbol VEGFA
Biologisk aktivitet Determined by its ability to stimulate the proliferation of human umbilical vein endothelial cells (HUVEC). The expected ED50 for this effect is 1.0-10.0 ng/ml
Konjugera Unconjugated
Rekombinant Recombinant
Sekvens APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
Innehåll och lagring -20°C
Uttryckssystem E. coli
Form Lyophilized
Renhet eller kvalitetsklass ≥ 98% by SDS-PAGE gel and HPLC analyses.
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