missing translation for 'onlineSavingsMsg'
Learn More

humanin Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 25885-1-AP-20UL

Additional Details : Weight : 0.00010kg

 View more versions of this product

Product Code. 16884435

  • 1656.73 SEK / 20µL
Estimated Shipment: 03-04-2024
to see stock.

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Humanin is a novel 24 A. A polypeptide identified in Alzheimer′s disease-affected brain. It is 99% homologous to mitochondrial 16s ribosomal RNA and functions as a novel neuroprotective and cytoprotective factor. It specifically inhibits neuronal cell death induced by beta-amyloids and Alzheimer′s disease causing FAD genes by competitively inhibiting access of FPRL1 receptor to beta-amyloids. It acts as an anti-apoptotic factor by binding to Bcl-2/Bax family of pro-apoptotic factors including Bax, Bak, Bid and BimEL and inhibits their pro-apoptotic activity. It activates JAK/STAT signaling pathway and is regulated by TRIM11. It interacts with IGFBP-3 and specifically blocks IGFBP-3 induced cell death in glioblastoma cells. Humanin is also expressed in colon and testis.
Specifications

Specifications

humanin
Polyclonal
Unconjugated
MT-RNR2
humanin, l rRNA, MTRNR2, RNR2
Rabbit
Antigen Affinity Chromatography
RUO
4550
-20°C
Liquid
Immunohistochemistry (Paraffin)
0.41 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q8IVG9
MT-RNR2
Peptide
20 μL
Primary
Human
Antibody
IgG
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers