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humanin Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1656.73 SEK - 4721.67 SEK
Specifications
| Antigen | humanin |
|---|---|
| Concentration | 0.41 mg/mL |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
16884435
|
Proteintech
25885-1-AP-20UL |
20 μL |
1656.73 SEK
20µL |
Estimated Shipment: 24-04-2024 Log in to see stock. |
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|
16874435
|
Proteintech
25885-1-AP-150UL |
150 μL |
4721.67 SEK
150µL |
Estimated Shipment: 24-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Humanin is a novel 24 A. A polypeptide identified in Alzheimer′s disease-affected brain. It is 99% homologous to mitochondrial 16s ribosomal RNA and functions as a novel neuroprotective and cytoprotective factor. It specifically inhibits neuronal cell death induced by beta-amyloids and Alzheimer′s disease causing FAD genes by competitively inhibiting access of FPRL1 receptor to beta-amyloids. It acts as an anti-apoptotic factor by binding to Bcl-2/Bax family of pro-apoptotic factors including Bax, Bak, Bid and BimEL and inhibits their pro-apoptotic activity. It activates JAK/STAT signaling pathway and is regulated by TRIM11. It interacts with IGFBP-3 and specifically blocks IGFBP-3 induced cell death in glioblastoma cells. Humanin is also expressed in colon and testis.Specifications
| humanin | |
| Immunohistochemistry (Paraffin) | |
| Unconjugated | |
| Rabbit | |
| Human | |
| Q8IVG9 | |
| 4550 | |
| Peptide | |
| Primary | |
| -20°C | |
| MT-RNR2 |
| 0.41 mg/mL | |
| Polyclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| humanin, l rRNA, MTRNR2, RNR2 | |
| MT-RNR2 | |
| IgG | |
| Antigen Affinity Chromatography | |
| Antibody |