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Proteintech HumanKine™ recombinant human IL-34 protein
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Kvantitet:
10 μg
100 μg
1000 μg
Beskrivning
IL-34 is a 6-α-helix, proinflammatory cytokine that serves as a ligand for colony-stimulating factor-1 receptor (CSF1R). It is expressed most abundantly by spleen cells. It primarily stimulates human peripheral blood monocyte proliferation and macrophage colony formation. It is also required for Langerhans cell and microglia development. IL-34 has been shown to play a protective role in cancer and Alzheimer’s disease, but it can promote the progression of several autoimmune, inflammatory, and metabolic diseases. As such IL-34 could be used as a biomarker to mark the progression of these diseases (PMID: 22579672, 27577879, 31940023).
Specifikationer
Specifikationer
| Tillträdesnummer | Q6ZMJ4 |
| Formulering | 50 mM Acetate pH 4.5 + 75 mM NaCl, See Certificate of Analysis for details |
| Gen-ID (Entrez) | 146433 |
| Molekylvikt (g/mol) | 68 and 38 kDa |
| Kvantitet | 1000 μg |
| Källa | HEK293 |
| Förvaringskrav | Lyophilized product should be stored at -20°C to -80°C until expiry date and (at Room Temperature for 2 weeks.) |
| Endotoxinkoncentration | <1 EU/μg |
| Specifik reaktivitet | Human |
| Rekombinant | Recombinant |
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