missing translation for 'onlineSavingsMsg'
Läs mer
Läs mer
Invitrogen™ ICAM-3 Monoclonal Antibody (MEM-171), Alexa Fluor™ 488

Beskrivning
This antibody recognizes an extracellular epitope in the D2 domain of CD50 (ICAM-3), a 120-130 kDa type I membrane protein (immunoglobulin supergene family) expressed on leukocytes, endothelial cells and Langerhans cells; it is negative on platelets and erythrocytes.
CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages; this process is involved in dialogue between dendritic cells and granulocytes.
Specifikationer
Specifikationer
| Antigen | ICAM-3 |
| Användningsområden | Flow Cytometry |
| Klassificering | Monoclonal |
| Klona | MEM-171 |
| Konjugera | Alexa Fluor 488 |
| Formulering | PBS with 0.2% BSA and 15mM sodium azide |
| Gen | ICAM3 |
| Genaccessionsnr. | P32942 |
| Gene Alias | CD50; CDw50; ICAM3; ICAM-3; ICAM-R; Intercellular adhesion molecule 3; intercellular adhesion molecule-3 |
| Gensymboler | ICAM3 |
| Visa mer |
Produkttitel
Genom att klicka på Skicka bekräftar du att du kan bli kontaktad av Fisher Scientific angående feedbacken du har lämnat i detta formulär. Vi kommer inte att dela din information för andra ändamål. All kontaktinformation som tillhandahålls ska också underhållas i enlighet med vår Sekretesspolicy.
Hittar du en möjlighet till förbättring?