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ICK Recombinant Human Protein

ICK Recombinant Human Protein

Brand:  Invitrogen PV6359

Additional Details : Weight : 0.01000kg

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Product Code. 15448993

  • 10180.00 SEK / 100µg


Estimated Shipment date
from Supplier 27-12-2017
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Disclaimers:

For Research Use Only. Not for use in diagnostic procedures.


Description

Description

ICK or intestinal cell kinase belongs to a very extensive family of proteins that share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. ICK encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. ICK localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. ICK purified from transfected human embryonic kidney cells undergoes autophosphorylation and phosphorylates a test protein. ICK plays a key role in development of central nervous, skeletal, and endocrine systems. Full-length recombinant human ICK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use

    Related Product:
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  • Specifications

    Specifications

    NP_055735.1
    Pharma and biopharma, protein assays and analysis, target and lead identification and validation
    ICK Recombinant Human Protein
    100μg
    For research use only. Not for use in diagnostic procedures
    ECO, MRK, KIAA0936, LCK2, MGC46090
    ICK was pre-diluted in enzyme dilution buffer and assayed in 5mM MOPS (pH 7.2), 2.5mM β-glycerol-phosphate, 5mM MgCl2, 0.4mM EDTA, 1mM EGTA, 0.05mM DTT, with 50μM ATP, trace [33P]-γ-ATP and 200μg/mL myelin basic protein (MBP) for 15 min.s at 30°
    ICK Recombinant Human Protein
    Human
    0.05mg/mL
    95.1kDa
    >75% by SDS-PAGE
    –68 to –85°C
    1 Each
    ICK Recombinant Human Protein
    Kinase assay
    5.5nmoles of phosphate transferred to myelin basic protein (MBP) per minute per mg of total protein at 30°C
    GST Tag
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