missing translation for 'onlineSavingsMsg'
Learn More

ID3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10389-1-AP-150UL

Additional Details : Weight : 0.00010kg

 View more versions of this product

Product Code. 16876743

  • 3313.85 SEK / 150µL
Estimated Shipment: 02-12-2021

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Members of the Id family of basic helix-loop-helix (bHLH) proteins include ID1, ID2, ID3 and ID4. They are ubiquitously expressed and dimerize with members of the class A and B HLH proteins. Due to the absence of the basic region, the resulting heterodimers cannot bind DNA. The ID-type proteins thus appear to negatively regulate DNA binding of bHLH proteins. Since ID1 inhibits DNA binding of E12 and Myo D, it apparently functions to inhibit muscle-specific gene expression. Under conditions that facilitate muscle cell differentiation, the ID protein levels fall, allowing E12 and/or E47 to form heterodimers with Myo D and myogenin, which in turn activate myogenic differentiation. It has been shown that expression of each of the ID proteins is strongly dependent on growth factor activation and that reduction of ID mRNA levels by antisense oligonucleotides leads to a delayed reentry of arrested cells into the cell cycle following growth factor stimulation.
Specifications

Specifications

ID3
0.4 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P41133, P41138, Q02535
1R21, bHLHb25, HEIR 1, HEIR1, ID3, Inhibitor of DNA binding 3
Rabbit
IgG
150 μL
-20°C
Primary
15903, 25585, 3399
Western Blot
Unconjugated
ID3
Liquid
ID3
ID3 Fusion Protein Ag0588
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Videos
SDS
Documents
Certificates
Special Offers

Special Offers