IL-2 Rat anti-Mouse, Clone: JES6-1A12, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 14-7022-85
Additional Details : Weight : 0.01000kg
DescriptionFiltration: 0.2 μm post-manufacturing filtered. Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
|PBS with 0.09% sodium azide; pH 7.2|
|Interleukin-2, T-cell growth factor, TCGF, Aldesleukin|
For Research Use Only.