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IL-31 Monoclonal Antibody (31SNEZE), eFluor™ 660, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 50-9319-42
Additional Details : Weight : 0.23750kg
Description
Description: This 31SNEZE monoclonal antibody reacts with human IL-31. Interleukin-31 (IL-31) is a recently-discovered member of the IL-6 family of cytokines. It is expressed by CD4+ T cells, particularly those with a Th2 phenotype, and mast cells. The IL-31 receptor is a heterodimer composed of one IL-31RA and one OSMR beta subunit. This receptor is constitutively expressed by various cells types, including macrophages, monocytes, eosinophils, keratinocytes, and epithelial cells. IL-31 receptor signaling leads to STAT3 activation and promotes the release of proinflammatory cytokines and chemokines, such as IL-1 beta, IL-6, IL-8, CXCL1, and CCL2. Over-expression of IL-31 is observed in patients with allergic asthma, allergic rhinitis, and atopic dermatitis, with a positive correlation between circulating levels and disease severity. Applications Reported: This 31SNEZE antibody has been reported for use in intracellular staining followed by flow cytometric analysis. Applications Tested: This 31SNEZE antibody has been pre-titrated and tested by intracellular staining followed by flow cytometric analysis of human peripheral blood lymphocytes. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.
IL-31 Monoclonal antibody specifically detects IL-31 in Human samples. It is validated for Flow Cytometry.Specifications
IL-31 | |
Monoclonal | |
5 μL/Test | |
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2 | |
Q6EBC2 | |
Il31 | |
Affinity chromatography | |
RUO | |
386653 | |
4° C, store in dark, DO NOT FREEZE! | |
Liquid |
Flow Cytometry | |
31SNEZE | |
eFluor 660 | |
Il31 | |
1700013B14Rik; IL31; IL-31; ILN; Interleukin; interleukin 31; interleukin-31 | |
Mouse | |
100 Tests | |
Primary | |
Human | |
Antibody | |
IgG2b κ |
For Research Use Only.