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IL-4 Mouse anti-Human, Clone: 8D4-8, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-7049-81

Additional Details : Weight : 0.01000kg

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Product Code. 15217997

  • 724.00 SEK / 50µg


Estimated Shipment
03-11-2020
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Description

Description

Filtration: 0.2 μm post-manufacturing filtered. Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
Specifications

Specifications

IL-4
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P05112
Interleukin-4, BSF1, IL-4, Lymphocyte stimulatory factor 1, MGC79402
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
ELISA
8D4-8
Unconjugated
IL4
Liquid
IL4
IgG1, kappa
50 μg
4° C
Primary
3565
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For Research Use Only.