missing translation for 'onlineSavingsMsg'
Learn More

IL-4 Mouse, anti-Human, R718, Clone: MP4-25D2, BD Horizon™

Mouse Monoclonal Antibody

2940.00 SEK - 4370.00 SEK

Specifications

Antigen IL-4
Clone MP4-25D2
Applications Flow Cytometry
Classification Monoclonal
Conjugate R718
View More Specs

Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17207774
View Documents
BD Biosciences
566981
25 Tests
2940.00 SEK
25 tests
Please to purchase this item. Need a web account? Register with us today!
17297764
View Documents
BD Biosciences
566980
100 Tests
4370.00 SEK
100 tests
Please to purchase this item. Need a web account? Register with us today!
Description

Description

The MP4-25D2 monoclonal antibody specifically binds to Interleukin-4 (IL-4). IL-4 is also known as Lymphocyte stimulatory factor 1, B cell stimulatory factor 1 (BSF-1), or B cell growth factor 1 (BCGF-1). IL-4 is produced by activated T cells, basophils, and mast cells. IL-4 is a multifunctional cytokine and growth factor that affects a variety of different target cell types. IL-4 can costimulate T cell proliferation and survival, as well as help drive Th2-like cell differentiation and effector functions. It costimulates B cell proliferation and survival, and can help B cells differentiate into IgG4- or IgE-producing cells. IL-4 can also diminish the proinflammatory functions of monocytes and macrophages. IL-4 exerts its biological effects by binding with high affinity to cell surface CD124 (IL-4Rα chain). CD124 forms signaling IL-4 receptor complexes with either CD132/common γ chain or CD213a1/IL-13Rα1 to form either Type I or Type II IL-4 Receptor complexes, respectively. The immunogen used to generate the MP4-25D2 hybridoma was purified recombinant human IL-4. This is a neutralizing antibody. The MP4-25D2 antibody has been reported to crossreact with IL-4 from rhesus monkeys. The use of the MP4-25D2 antibody for epitope mapping of human IL-4 has been described.

Specifications

Specifications

IL-4
Flow Cytometry
R718
Mouse
Human
Refrigerate Upon Arrival
MP4-25D2
Monoclonal
Liquid
RUO
Primary
Videos
SDS
Documents

Documents

Product Certifications
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title
IL-4 Mouse, anti-Human, R718, Clone: MP4-25D2, BD Horizon™

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.