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IL-4 Rat anti-Mouse, FITC, Clone: BVD6-24G2, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-7042-81

Additional Details : Weight : 0.25000kg

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Product Code. 15218349

  • 1936.00 SEK / 50µg

Estimated Shipment
21-07-2021

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Description

Description

Description: The BVD6-24G2 antibody reacts with mouse interleukin-4 (IL-4), a 14 kDa cytokine secreted by Th2 cells. Applications Reported: BVD6-24G2 has been reported for use in intracellular flow cytometric analysis. Applications Tested: This BVD6-24G2 antibody is offered in 2 formats: - μg size: has been tested by intracellular staining and flow cytometric analysis of restimulated mouse splenocytes cultures. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. - test size: has been pre-titrated and tested by intracellular staining and flow cytometric analysis of restimulated mouse splenocytes cultures. Refer to catalog number suffix on the vial for amount to use per test: -41 is 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered.

Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
Specifications

Specifications

IL-4
Monoclonal
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P07750
Interleukin-4, BSF1, IL-4, Lymphocyte stimulatory factor 1, MGC79402
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
BVD6-24G2
FITC
Il4
Liquid
Il4
IgG1, kappa
50 μg
4° C, store in dark, DO NOT FREEZE!
Primary
16189
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SDS
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For Research Use Only.