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IL-6 Monoclonal Antibody (MQ2-13A5), Functional Grade, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

1116.00 SEK - 18870.00 SEK

Specifications

Antigen IL-6
Clone MQ2-13A5
Concentration 1 mg/mL
Applications ELISA, Functional Assay, Neutralization
Classification Monoclonal
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Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15218757
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Affymetrix eBioscience
16-7069-81
50 μg
1116.00 SEK
50µg
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Estimated Shipment: 25-04-2024
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15228757
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Affymetrix eBioscience
16-7069-85
500 μg
3235.00 SEK
500µg
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15567806
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Affymetrix eBioscience
16-7069-38
5 mg
18870.00 SEK
5mg
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Estimated Shipment: 25-04-2024
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Description

Description

Description: The MQ2-13A5 antibody reacts with human interleukin-6 (IL-6), a 21-28 kDa cytokine secreted by a variety of cell types. Applications Reported: This MQ2-13A5 antibody has been reported for use in cytokine neutralization, ELISPOT, and ELISA capture. Applications Tested: The MQ2-13A5 antibody has been tested for neutralizing IL-6 binding and biological activity. Storage and handling: Use in a sterile environment. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC.

IL-6 is a gene that encodes a cytokine that plays a role in inflammation and the maturation of B cells. The protein produced by this gene is an endogenous pyrogen that can induce fever in people with autoimmune diseases or infections. The gene is primarily expressed at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). Diseases associated with IL6 include Kaposi Sarcoma and Rheumatoid Arthritis, Systemic Juvenile.
Specifications

Specifications

IL-6
1 mg/mL
Monoclonal
Liquid
RUO
PBS with no preservative; pH 7.2
B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6
Il6
Primary
4° C
Il6
MQ2-13A5
ELISA, Functional Assay, Neutralization
Functional Grade
Rat
Human
P05231
3569
IgG1 κ
Affinity chromatography
Antibody
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