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Invitrogen™ IL1F6 Polyclonal Antibody

Produktkod. 16333915
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100 μL
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Produktkod. Kvantitet
16333915 100 μL
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Produktkod. 16333915 Leverantör Invitrogen™ Leverantörsnummer PA587054

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Beskrivning

Rabbit Polyclonal Antibody

Purity is > 95% by SDS-PAGE.

The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36alpha (IL-1F6), beta (IL-1F8), and gamma (IL-1F9). IL-36alpha is highly expressed in psoriatic plaques, as are IL-36beta and IL-36gamma, and is the only IL-1 family member found to be expressed by T cells, as well as monocytes and B cells. Primarily found in skin and lymphoid tissues, IL-36alpha is also found to a lesser extent in tissues of the fetal brain, trachea, stomach, and intestine. IL-36alpha signals through a combination of the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells, and the widely expressed IL-RAcP (IL-1 receptor accessory protein). IL-36alpha also functions as an agonist of NF-kappaB and MAPK pathways, and induces the production of proinflammatory cytokines and chemokines, including IL-6, IL-8, BD-2, and BD-3.
TRUSTED_SUSTAINABILITY

Specifikationer

Antigen IL1F6
Användningsområden Western Blot
Klassificering Polyclonal
Koncentration 1 mg/mL
Konjugera Unconjugated
Formulering PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gen IL36A
Genaccessionsnr. Q9JLA2, Q9UHA7
Gene Alias FIL1; FIL1 epsilon; FIL1(EPSILON); Fil1e; Fil1epsilon; IL-1 epsilon; IL1(EPSILON); Il1e; Il1f6; IL-1F6; IL-1F6 (FIL-1-epsilon); Il1f9; Il1h1; IL-1H1; IL1RP2; Il36a; Interleukin; interleukin 1; interleukin 1 family, member 6; interleukin 1 family, member 6 (epsilon); interleukin 1 family, member 9; interleukin 1, epsilon; interleukin 36, alpha; interleukin-1 epsilon; Interleukin-1 family member 6; interleukin-1 homolog 1; Interleukin-36; Interleukin-36 alpha
Gensymboler Il1f6, IL36A
Värd art Rabbit
Immunogen Recombinant fusion protein of human IL36A.
Reningsmetod Antigen affinity chromatography
Kvantitet 100 μL
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 27179, 296541, 54448
Målarter Human, Mouse, Rat
Innehåll och lagring Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttyp Antibody
Form Liquid
Isotyp IgG
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Produkttitel
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