IRF4 Rat anti-Human, Mouse, Clone: 3E4, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 14-9858-80
Additional Details : Weight : 0.01000kg
DescriptionPurity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. The IRF (interferon regulatory factor) family of transcription factors are characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. IRF4 is lymphocyte specific and negatively regulates toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found.
|PBS with 0.09% sodium azide; pH 7.2|
For Research Use Only.