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IRSp53 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11087-2-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16827933

  • 1236.20 SEK / 20µL
Estimated Shipment: 08-12-2021

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Description

Description

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal domit neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Specifications

Specifications

IRSp53
0.4 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q6GMN2, Q8BKX1, Q9UQB8
BAI associated protein 2, BAI1 associated protein 2, BAIAP2, BAP2, Fas ligand associated factor 3, FLAF3, Insulin receptor substrate p53, IRS 58, IRSp53, IRSp53/58, Protein BAP2
Rabbit
IgG
20 μL
-20°C
Primary
10458, 108100, 117542
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
Unconjugated
BAIAP2
Liquid
BAIAP2
IRSp53 Fusion Protein Ag1552
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Rat, Mouse
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