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Itraconazole, 98%

Produktkod. 15497729
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Produktkod. 15497729 Leverantör Thermo Scientific Alfa Aesar Leverantörsnummer J66390.06
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Beskrivning

CAS: 84625-61-6 | C35H38Cl2N8O4 | 705.64 g/mol

Itraconazole is a triazole antifungal agent. It is used to inhibit cytochrome P-450-dependent enzymes and ergosterol synthesis. It has been used against histoplasmosis, blastomycosis, cryptococcal meningitis, and aspergillosis. It?s different formulations are used to study Candida strains in murine invasive infections. It has been used to study proliferative changes of the forestomach mucosa in alloxan-induced diabetic rats..

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Itraconazole is a triazole antifungal agent. It is used to inhibit cytochrome P-450-dependent enzymes and ergosterol synthesis. It has been used against histoplasmosis, blastomycosis, cryptococcal meningitis, and aspergillosis. It′s different formulations are used to study Candida strains in murine invasive infections. It has been used to study proliferative changes of the forestomach mucosa in alloxan-induced diabetic rats..

Solubility
Insoluble in water. Solube in chloroform at 50 mg/ml. Slightly soluble in ethanol or methanol

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
TRUSTED_SUSTAINABILITY

Kemiska identifierare

CAS 84625-61-6
Molekylformel C35H38Cl2N8O4
Molekylvikt (g/mol) 705.64
MDL-nummer MFCD00870168,MFCD00941396
InChI-nyckel VHVPQPYKVGDNFY-ZPGVKDDISA-N
Synonym Oriconazole; R51211
PubChem CID 45039617
IUPAC-namn 1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one
LEDER CCC(C)N1N=CN(C1=O)C1=CC=C(C=C1)N1CCN(CC1)C1=CC=C(OC[C@H]2CO[C@@](CN3C=NC=N3)(O2)C2=CC=C(Cl)C=C2Cl)C=C1

Specifikationer

Kemiskt namn eller material Itraconazole
Typ Itraconazole
Fysisk form Powder
Smältpunkt 166°C
Färg White
Kvantitet 5 g
Flampunkt >110°C (230°F)
Merck Index 14,5245
Löslighetsinformation Insoluble in water; Solube in chloroform at 50mg/ml; Slightly soluble in ethanol or methanol
Formel vikt 705.63
Procent renhet 98%
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RUO – Research Use Only

Produkttitel
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