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IWS1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 16943-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16826734

  • 3313.85 SEK / 150µL
Estimated Shipment: 30-11-2021

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Description

Description

Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.
Specifications

Specifications

IWS1
0.25 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q3SWT4, Q8C1D8, Q96ST2
IWS1, IWS1 homolog (S. cerevisiae), IWS1 like protein, IWS1L, Protein IWS1 homolog
Rabbit
IgG
150 μL
-20°C
Primary
291705, 55677, 73473
Immunoprecipitation, Western Blot
Unconjugated
IWS1
Liquid
Iws1
IWS1 Fusion Protein Ag10554
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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