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Invitrogen™ Jagged1 Monoclonal Antibody (J.841.5)
Rabbit Monoclonal Antibody
Brand: Invitrogen™ MA515012
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Beskrivning
It is not recommended to aliquot this antibody. This antibody is not cross-reactive with Jagged2.
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
Specifikationer
| Jagged1 | |
| Monoclonal | |
| 78 μg/mL | |
| 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5 | |
| P78504, Q9QXX0 | |
| JAG1 | |
| Synthetic peptide corresponding to residues surrounding Glu1140 (intracellular region) of human Jagged1. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
| Immunoprecipitation, Western Blot | |
| J.841.5 | |
| Unconjugated | |
| JAG1 | |
| ABE2; AGS; AHD; AWS; CD339; Gsfabe2; HJ1; Htu; JAG1; jagged 1; jagged canonical Notch ligand 1; Jagged1; JAGL1; Ozz; protein jagged-1; Ser-1; Serrate-1 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 16449, 182 | |
| -20°C | |
| Liquid |
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