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  7. JP 1302 dihydrochloride, Tocris Bioscience™

JP 1302 dihydrochloride, Tocris Bioscience™

Product Code. 18085582
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Quantity:
10 mg
50 mg
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Description

Potent and selective α2C antagonist

α2C-adrenoceptor antagonist that displays ∽ 50-fold selectivity over other α2-adrenoceptor subtypes (Ki values are 28, 1470, 1700 and 3150 nM for human α2C, α2B, α2D and α2A subtypes respectively). Potently antagonizes adrenalin-stimulated 35GTPγS binding in vitro (KB = 16 nM) and produces antidepressant and antipsychotic-like effects in vivo.

Chemical Identifiers

CAS 1259314-65-2
Molecular Formula C24H26Cl2N4
Molecular Weight (g/mol) 441.4
InChI Key VVZOADYFJAJZGL-UHFFFAOYSA-N
Synonym jp 1302 dihydrochloride, n-4-4-methyl-1-piperazinyl phenyl-9-acridinamine dihydrochloride, n-4-4-methyl-1-piperazinyl phenyl-9-acridinaminedihydrochloride, n-4-4-methylpiperazin-1-yl phenyl acridin-9-amine dihydrochloride
PubChem CID 49855035
IUPAC Name N-[4-(4-methylpiperazin-1-yl)phenyl]acridin-9-amine;dihydrochloride
SMILES CN1CCN(CC1)C2=CC=C(C=C2)NC3=C4C=CC=CC4=NC5=CC=CC=C53.Cl.Cl

Specifications

Quantity 50 mg
Formula Weight 441.4
Percent Purity >99%
Chemical Name or Material JP 1302 dihydrochloride
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