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Kanamycin monosulfate, Cell Culture Grade, Thermo Scientific™

Kanamycin monosulfate, CAS # 25389-94-0, is an aminoglycoside sulfate salt with antibacterial activity.

Brand:  Thermo Scientific Alfa Aesar J60668.06

Additional Details : CAS Number : 25389-94-0 Weight : 0.00500kg

Quantity 5g

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Product Code. 15463399

  • 956.51 SEK / 5g
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Description

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description

• Kanamycin monosulfate is the sulfate salt form of kanamycin A

• It was isolated from Streptomyces kanamyceticus

• This compound inhibits translocation during protein biosynthesis. It binds to the 30S ribosomal subunit, causing misreading of the mRNA sequence

Application

• Kanamycin monosulfate shows antibacterial activity. It is effective against gram-positive and gram-negative bacteria, as well as Mycoplasma species

• This compound is also involved in translating prokaryotic ribosomes

• In molecular biology experiments, it is commonly used to select and isolate transformants expressing the kanamycin resistance gene, and plants that have the NPT II (APH3) gene incorporated

Literature References

Patel, K. N.; Limgavkar, R. S.; Raval, H. G.; Patel, K. G.; Gandhi, T. R. High-Performance Liquid Chromatographic Determination of Cefalexin Monohydrate and Kanamycin Monosulfate with Precolumn Derivatization. J. Liq. Chromatogr. Related Technol. 2015, 38 (6), 716-721.

Chi, Z.; Rong, Y. J.; Li, Y.; Tang, M. J.; Chi, Z. M. Biosurfactins production by Bacillus amyloliquefaciens R3 and their antibacterial activity against multi-drug resistant pathogenic E. coli. Bioprocess. Biosyst. Eng. 2015, 38 (5), 853-861.

Specifications

Chemical Identifiers

25389-94-0
582.575
OOYGSFOGFJDDHP-IZQIRFRQSA-N
134129479
C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N.OS(=O)(=O)O
C18H38N4O15S
MFCD00070253
Kanamycin A
(2R,3S,4S,5S,6R)-2-(aminomethyl)-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5R,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol;sulfuric acid

Specifications

Kanamycin monosulfate
C18H38N4O15S
14,5281
Soluble in water at 10mg/ml
C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N.OS(=O)(=O)O
582.575
582.58
Cell Culture
5g
25389-94-0
MFCD00070253
Kanamycin A
OOYGSFOGFJDDHP-IZQIRFRQSA-N
(2R,3S,4S,5S,6R)-2-(aminomethyl)-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5R,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol;sulfuric acid
134129479
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