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KIT [V559D T670I] Recombinant Human Protein, Invitrogen™

KIT (c-KIT) is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Recombinant human KIT V559D T670I (544-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

3605.00 SEK - 55100.00 SEK

Specifications

Host Species Human
Protein Tag GST Tag
Recombinant Yes
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Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15418963
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Invitrogen
PV6316
10μg
3605.00 SEK
10µg
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Estimated Shipment: 11-02-2022
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15428963
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Invitrogen
PV6317
100μg
12320.00 SEK
100µg
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Estimated Shipment: 11-02-2022
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15438963
View Documents Promotion Details
Invitrogen
PV6318
1mg
55100.00 SEK
1mg
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Estimated Shipment: 11-02-2022
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Description

Description

KIT was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT together with its ligand regulates growth and activation of a variety of hemopoietic and non-hemopoietic cells. Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Recently, deregulation of the KIT receptor TK by the prevalent activation loop mutation D816V has served as a focal point in therapeutic strategies aimed at curbing neoplastic mast cell growth.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use
Specifications

Specifications

Human
GST Tag
Yes
SDS
Product Certifications