KLRG1 Mouse anti-Human, PerCP-eFluor 710, Clone: 13F12F2, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 46-9488-42
Additional Details : Weight : 0.23750kg
DescriptionThis 13F12F2 monoclonal antibody reacts with human killer cell lectin-like receptor subfamily G, member 1 (KLRG1), a type II transmembrane inhibitor receptor of the C-type lectin superfamily that contains an ITIM domain. This inhibitory receptor is expressed on subsets of gamma-delta T cells, NK (CD56dim), CD8+ and CD4+ T Cells. KLRG1 is expressed primarily by cells with an effector/memory phenotype that are short-lived, but capable of immediate effector cell function. Cadherin-E, -N, and -R are ligands for KLRG1. Cadherin/KLRG1 interaction inhibits cytolytic activity and proliferation. The percentage of KLRG1 positive cells can vary considerably, depending on antigen experience.
The clones 13F12F2 and 13A2 appear to recognize a similar epitope based on cross-blocking studies.
|Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage|
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|