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Epredia™ Lab Vision™ β-Catenin Rabbit Monoclonal Antibody
Ensure accurate and reproducible results in immunohistochemistry applications with this antibody, part of a comprehensive antibody portfolio.
Brand: Epredia™ RM-2101-S
This item is not returnable.
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Description
The catenins (α, β and γ) are ubiquitously expressed cytoplasmic proteins associated with E-cadherin at cellular junctions. β-catenin also binds to N-cadherin and co-immunoprecipitates with APC. Cadherin/catenin complexes are linked to the cytoskeleton via a direct association between α-actinin and α-catenin. Increased tyrosine phosphorylation can disrupt catenin-cadherin complexes, influencing cellular adhesion. Mutations in the catenin gene, CTNNB1, have been implicated in its accumulation and various forms of carcinomas.Host Species: Rabbit
Clone: E247
Species Reactivity: Human. Others not known.
Immunogen: A synthetic peptide derived from near the N-terminus of human β-catenin
Molecular Weight: 92 kDa
Positive Control: Breast CA
Cellular Localization: Cell Membrane
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
Specifications
| Catenin, beta | |
| Monoclonal | |
| Unconjugated | |
| A synthetic peptide derived from near the N-terminus of human beta-catenin | |
| IVD | |
| Primary | |
| Concentrated |
| Immunohistochemistry (Paraffin) | |
| E247 | |
| Rabbit | |
| 1 mL | |
| Cancer and Tumor Biology | |
| Human |