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CD36/GPIIIb/GPIV Ab-3 Mouse Monoclonal Antibody, Epredia™
Ensure accurate, reproducible results in immunohistochemistry , immunofluorescence, flow cytometry and function blocking experiment.
Brand: Epredia MS-756-P
Additional Details : Weight : 0.00100kg
Description
CD36 (also known as platelet glycoprotein IV, OKM5-antigen, or platelet glycoprotein IIIb) acts as a receptor for thrombospondin (TSP), collagen, falciparum malaria parasitized erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL), and apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischaemia observed in sickle cell disease and cerebral malaria. Ab-3 blocks adhesion of P. falciparum parasitized red blood cells to CD36 and strongly inhibits collagen-induced platelet aggregation.Host Species: Mouse
Clone: 185-1G2
Isotype: IgG2a/κ
Species Reactivity: Human. Others not tested.
Epitope: Not determined
Immunogen: Stimulated human leukocytes
Molecular Weight: 88 kDa
Positive Control: Tonsil
Cellular Localization: Membrane
Recommended for:
- Immunohistochemistry (Frozen only)
- Western Blotting (Not suitable)
- Immunofluorescence
- Flow Cytometry
- Function Blocking
Note:
USA: RUO; Int'l: RUO
Specifications
CD36/GPIIIb/GPIV Ab-3 | |
Monoclonal | |
200μg/mL | |
Mouse | |
1 mL | |
Hematopoietic | |
Human | |
IgG2a κ |
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen) | |
185-1G2 | |
Unconjugated | |
Stimulated human leukocytes | |
RUO | |
Primary | |
Concentrated |