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Lactoferrin, clone: B97, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-6604-80

Additional Details : Weight : 0.01000kg

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Product Code. 15277917

  • 738.00 SEK / 25µg


EU Stock 2
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Description

Description

It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. Lactoferrin (LF) is an iron binding glycoprotein. LF consists of a single polypeptide chain (approximately 80 kDa) folded into two structurally homologous lobes, each of which can reversibly bind one ferric ion (Fe3+). LF is found in external fluids, including milk and mucosal secretions, and is a prominent component of secondary granuals of neutrophils. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. LTF acts as a major first line defense against microbial infections, partly due to its ability to efficiently bind to and hence remove Fe3+ from the environment, but studies have also shown that LTF possesses bactericidal properties and proteolytic activity, capable of cleaving arginine-rich sequences within microbial proteins. Three isoforms of LTF have been identified: LTF-alpha, LTF-beta and LTF-gamma and receptors for LTF are expressed in the gastrointestinal tract, by macrophages, lymphocytes, neutrophils and platelets and also by some bacteria.
Specifications

Specifications

lactoferrin
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P02788
CKRX, GIG12, HLF2, Homo sapiens chemokine receptor X, Kaliocin 1
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Immunohistochemistry (Paraffin), Western Blot
B97
Unconjugated
LTF
Liquid
LTF
IgG1
25 μg
4° C
Primary
4057
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