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Lactoferrin Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10933-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16827653

  • 1236.20 SEK / 20µL
Estimated Shipment: 08-12-2021

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Description

Description

Lactoferrin (LF) is an iron binding glycoprotein. LF consists of a single polypeptide chain (approximately 80 kDa) folded into two structurally homologous lobes, each of which can reversibly bind one ferric ion (Fe3+). LF is found in external fluids, including milk and mucosal secretions, and is a prominent component of secondary granuals of neutrophils. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. LTF acts as a major first line defense against microbial infections, partly due to its ability to efficiently bind to and hence remove Fe3+ from the environment, but studies have also shown that LTF possesses bactericidal properties and proteolytic activity, capable of cleaving arginine-rich sequences within microbial proteins. Three isoforms of LTF have been identified: LTF-alpha, LTF-beta and LTF-gamma and receptors for LTF are expressed in the gastrointestinal tract, by macrophages, lymphocytes, neutrophils and platelets and also by some bacteria.
Specifications

Specifications

Lactoferrin
0.31 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P02788
GIG12, HLF2, Lactoferrin, lactotransferrin, LF, LTF, Talalactoferrin
Rabbit
IgG
20 μL
-20°C
Primary
4057
Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation
Unconjugated
LTF
Liquid
LTF
Lactoferrin Fusion Protein Ag1379
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
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