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![Thermo Scientific LanthaScreen Tb-anti-PRAS40 [pSer183] Antibody 1 mg:Antibodies](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-650.jpg)
Thermo Scientific™ LanthaScreen™ Tb-anti-PRAS40 [pSer183] Antibody
For use in combination with the LanthaScreen™ PRAS40 HEK293E cell line (K1528) to evaluate inhibitors in medium to high throughput screening applications.
Brand: Thermo Scientific™ PV5579
This item is not returnable.
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Description
- PRAS40 (Proline-rich AKT substrate, 40 kDa) is a cytosolic protein that is phosphorylated at position Ser183
- It has been shown to bind to the mTORC1 complex and inhibit downstream signaling (i.e., phosphorylation of 4E-BP1 or p70S6K)
- For use in combination with the LanthaScreen™ PRAS40 HEK293E cell line (K1528) to evaluate inhibitors in medium to high throughput screening applications
Specifications
| Tb (Terbium)/Lanthanide Chelates | |
| Terbium-labeled pPRAS40 (pSer183) antibody in HEPES buffered saline. Store at -20°C. | |
| Human | |
| End Point | |
| Ser/Thr Kinases |
| 1 mg | |
| 340/90, 520 | |
| Dry Ice | |
| Hu | |
| LanthaScreen™ |
For Research Use Only. Not for use in diagnostic procedures.