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Invitrogen™ LanthaScreen™ Tb-p4E-BP1 (pThr46) Antibody Kit
A part of the PI3K/AKT Pathway, 4E-BP1 (EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1) is a cytosolic protein that is phosphorylated at Thr46 by mTORC1 upon stimulation of the pathway.
Brand: Invitrogen™ PV4757
This item is not returnable.
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Description
A part of the PI3K/AKT Pathway, 4E-BP1 (EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1) is a cytosolic protein that is phosphorylated at Thr46 by mTORC1 upon stimulation of the pathway.
For use in combination with the GFP-4E-BP1 physiological protein substrate (Cat. No. PV4759) to evaluate inhibitors in medium to high throughput screening applications. An optimized mTor assay buffer (PV4794) is also available.
Specifications
| Serine/threonine kinase | |
| 0.52mg/mL | |
| 150kDa | |
| RUO | |
| Primary | |
| Terbium-labeled anti-4E-BP1 [pThr46] antibody in HEPES buffered saline. Store at -20°C. |
|
| Biochemical terbium phospho-specific activity | |
| 340/490, 520 nm | |
| Dry Ice | |
| Hu | |
| Serine/Threonine Kinases | |
| FRAP1 (mTOR), FRAP1 (mTOR) |
| Kinase Assay, Enzyme and Protein Activity Assays, Kinase Assay | |
| Tb (Terbium)/GFP (EmGFP) | |
| 25 μg | |
| Target and Lead Identification and Validation | |
| 1 Kit(s) | |
| 150,000 Da | |
| 384-well Plate | |
| Human | |
| End Point | |
| mTOR, FRAP1 | |
| TR-FRET | |
| LanthaScreen™ |
For Research Use Only. Not for use in diagnostic procedures.