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Thermo Scientific Chemicals Lovastatin, 98%

Catalog Number p-7077757
514.57 SEK valid until 2024-03-29
Use promo code "21615" to get your promotional price.


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Quantity:
5 g
25 g
100 g
This item is not returnable. View return policy
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”21615” to get your promotional price
75330-75-5
C24H36O5
404.55
MFCD00072164
PCZOHLXUXFIOCF-BXMDZJJMSA-N
lovastatin, mevinolin, mevacor, monacolin k, lovalip, altoprev, lovalord, mevinacor, nergadan, 6alpha-methylcompactin
53232
CHEBI:40303
[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate
CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12
This item is not returnable. View return policy
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”21615” to get your promotional price
75330-75-5
C24H36O5
404.55
MFCD00072164
PCZOHLXUXFIOCF-BXMDZJJMSA-N
lovastatin, mevinolin, mevacor, monacolin k, lovalip, altoprev, lovalord, mevinacor, nergadan, 6alpha-methylcompactin
53232
CHEBI:40303
[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate
CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12

Lovastatin, CAS # 75330-75-5, is a cholesterol lowering compound and inhibitor of HMG-CoA reductase, a rate limiting enzyme in cholesterol synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

Applications

• It blocks product ion of mevalonate, a critical compound in the production of cholesterol and isoprenoids

• It can increase cellular resistance to anticancer agents such as doxorubicin • It can induce apoptosis in myeloma cells

• It can cause cell cycle arrest in G1 and G2/M phase

• It also blocks PDGF receptor tyrosine phosphorylation and MAP kinase activation by PDGF

TRUSTED_SUSTAINABILITY
Melting Point 175.0°C
Infrared Spectrum Authentic
Assay Percent Range 97.5% min. (HPLC)
Quantity 5 g
Solubility Information Solubility in water: insoluble. Other solubilities: less soluble in ethanol, soluble in chloroform and acetone
Formula Weight 404.54
Percent Purity 98%
Chemical Name or Material Lovastatin
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Product Identifier
  • Lovastatin
Signal Word
  • Warning
Hazard Category
  • Carcinogenicity Category 2
  • Reproductive toxicity Category 2
  • Respiratory sensitiser Category 1
Hazard Statement
  • H351-Suspected of causing cancer.
  • H361d-Suspected of damaging the unborn child.
  • H317-May cause an allergic skin reaction.
Precautionary Statement
  • P201-Obtain special instructions before use.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.

RUO – Research Use Only

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