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Invitrogen™ LRRK2 G2019S Full Length Protein

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which codes for a multidomain protein kinase, are considered the most common genetic cause of late-onset autosomal-dominant Parkinson's disease.

Brand:  Invitrogen™ A15201

Additional Details : Weight : 0.01000kg

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Product Code. 15458363

  • 2830.00 SEK / 100µg


Estimated Shipment date
from Supplier 12-03-2018
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Description

Description

This full-length, purified and active LRRK2 G2019S mutant protein may be useful in research to better understand the most common Parkinson's disease-relevant mutant, as well as to explore the mechanisms underlying the disease.

  • Increase disease relevance by interrogating a purified and active full-length LRRK2 protein
  • Uncover novel compounds or hits specific to the full-length form
  • Advance Parkinson 's research using the full-length protein and validated assays
Specifications

Specifications

NP_940980.3
288kDa
Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. If properly stored, this product is guaranteed for 6 months from date of purchase.

Suspended in: 50 mM Tris (pH 7.5), 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton®X–100, 2 mM DTT, and 50% glycerol.
AURA17, DARDARIN, PARK8, RIPK7, ROCO2
Mammalian
Human
LanthaScreen® Kinase Activity Assays|Target & Lead Identification & Validation|Kinase Biology|Biochemical Kinase Assays|Protein Biology|Enzyme & Protein Activity Assays|Kinase Activity|Protein Assays and Analysis|Industrial & Applied Science|Pharma & Biopharma
100μg
Full Length
Kinase Assay
LRRK Kinase Family
DYKDDDDK
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