Invitrogen™ LRRK2 G2019S Full Length Protein
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which codes for a multidomain protein kinase, are considered the most common genetic cause of late-onset autosomal-dominant Parkinson's disease.
Brand: Invitrogen™ A15201
Additional Details : Weight : 0.01000kg
This full-length, purified and active LRRK2 G2019S mutant protein may be useful in research to better understand the most common Parkinson's disease-relevant mutant, as well as to explore the mechanisms underlying the disease.
- Increase disease relevance by interrogating a purified and active full-length LRRK2 protein
- Uncover novel compounds or hits specific to the full-length form
- Advance Parkinson 's research using the full-length protein and validated assays
|Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. If properly stored, this product is guaranteed for 6 months from date of purchase.
Suspended in: 50 mM Tris (pH 7.5), 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton®X–100, 2 mM DTT, and 50% glycerol.
|AURA17, DARDARIN, PARK8, RIPK7, ROCO2|
|LanthaScreen® Kinase Activity Assays|Target & Lead Identification & Validation|Kinase Biology|Biochemical Kinase Assays|Protein Biology|Enzyme & Protein Activity Assays|Kinase Activity|Protein Assays and Analysis|Industrial & Applied Science|Pharma & Biopharma|
|LRRK Kinase Family|