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LRRK2 [G2019S] Recombinant Human Protein

LRRK2 [G2019S] Recombinant Human Protein

Brand:  Invitrogen PR8764C

UNSPSC : 12352204

Additional Details : Weight : 0.01000kg

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Product Code. 15468683

  • 20540.00 SEK / 100µg


Estimated Shipment date
from Supplier 07-09-2017
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Disclaimers:

For Research Use Only. Not for use in diagnostic procedures.


Description

Description

LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in this gene have been associated with Parkinson's disease. The G2019S mutation of LRRK2 is associated with an increase in catalytic activity.

Related Links:
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  • Specifications

    Specifications

    NP_940980.2, G2019S
    Protein assays and analysis
    Frozen
    LRRK2 [G2019S] Recombinant Human Protein
    100μg
    For research use only. Not for use in diagnostic procedures
    LRRK2 G2019S
    LRRK2 G2019S was pre-diluted in enzyme dilution buffer and assayed in 20mM Tris (pH 7.5), 10mM MgCl2, 1mM EGTA, 1mM Na3VO4, 5mM β- glycerophosphate, 2mM DTT, 0.02% Polysorbate 20, 100μM ATP, 250μM ERM (LRRKtide) peptide substrate (RLGRDKYKTLRQIRQ) (PV5093) and trace [32P]-γ-ATP for 10 minutes at 30°C
    Baculovirus
    Amino acids 970-2527
    260nmoles of phosphate transferred to ERM (LRRKtide) peptide substrate (RLGRDKYKTLRQIRQ) (PV5093) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 2.08μg/mL
    GST Tag
    0.26mg/mL
    Frozen
    204.9kDa
    85% by SDS-PAGE
    –80°C
    1 Each
    LRRK2 [G2019S] Recombinant Human Protein
    Kinase assay
    LRRK
    LRRK2 [G2019S] Recombinant Human Protein
    Human