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  5. Tocris Bioscience™ LW 6

Tocris Bioscience™ LW 6
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Product Code. 18736206
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Kvantitet:
10 mg
50 mg
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Product Code. 18736206

Brand: Tocris Bioscience™ 6322/50

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Description

Malate dehydrogenase-2 (MDH2) inhibitor; also inhibits HIF-1α

LW 6 is a malate dehydrogenase-2 (MDH2) inhibitor (IC50 = 6.3 μM). Also inhibits HIF-1α. Prevents accumulation of HIF-1α in Hep3B cells under hypoxic conditions (IC50 = 2.6 μM) with resulting decrease in expression of HIF-1α target genes VEGF and EPO. Inhibits proliferation of activated human T cells ex vivo.
TRUSTED_SUSTAINABILITY

Specifications

Kemiskt namn eller material Methyl 4-hydroxy-3-[[2-(4-tricyclo[3.3.1.13,7 ]dec-1-ylphenoxy)acetyl]amino]benzoate
CAS 934593-90-5
Kvantitet 50 mg
Mål Dehydrogenase Inhibitors
Molekylformel C26H29NO5
Renhet 0.98
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